Nfe2l1^tm1.2Mym
Targeted Allele Detail

Summary

• Symbol: Nfe2l1^tm1.2Mym
• Name: nuclear factor, erythroid derived 2,-like 1; targeted mutation 1.2, Masayuki Yamamoto
• MGI ID: MGI:7524669
• Gene: Nfe2l1 Location: Chr11:96708240-96720794 bp, - strand Genetic Position: Chr11, 60.12 cM, cytoband D-E
• Alliance: Nfe2l1^tm1.2Mym page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92262
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and a floxed neo cassette followed by an IRES-EGFP replaces the non-coding portion of exon 4. Cre-mediated recombination removed the selection cassette. (J:92262)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nfe2l1 Mutation: 40 strains or lines available

References

• Original: J:92262 Shimizu E, et al., Role of a NK receptor, KLRE-1, in bone marrow allograft rejection: analysis with KLRE-1-deficient mice. Blood. 2004 Aug 1;104(3):781-3
• All: 1 reference(s)