Spp1tm1.1Jkbs
Targeted Allele Detail
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Symbol: |
Spp1tm1.1Jkbs |
Name: |
secreted phosphoprotein 1; targeted mutation 1.1, Tatjana C Jakobs |
MGI ID: |
MGI:7524675 |
Synonyms: |
Spp1GFPfl |
Gene: |
Spp1 Location: Chr5:104582984-104588916 bp, + strand Genetic Position: Chr5, 50.68 cM
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Alliance: |
Spp1tm1.1Jkbs page
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Germline Transmission: |
Earliest citation of germline transmission:
J:335751
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Conditional ready, Reporter) |
Mutation: |
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Insertion
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Mutation details: The targeting vector is designed to contain (from 5' to 3';) a loxP site and a self-excising neomycin selection cassette placed upstream of exon 4, an enhanced green fluorescent protein sequence, a stop cassette, a second loxP site, and a tdTomato sequence with a stop cassette placed downstream of exon 7.
(J:335751)
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Original: |
J:335751 Li S, et al., Secreted phosphoprotein 1 slows neurodegeneration and rescues visual function in mouse models of aging and glaucoma. Cell Rep. 2022 Dec 27;41(13):111880 |
All: |
1 reference(s) |
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