About   Help   FAQ
Tph2tm1Kry
Targeted Allele Detail
Summary
Symbol: Tph2tm1Kry
Name: tryptophan hydroxylase 2; targeted mutation 1, Gerard Karsenty
MGI ID: MGI:7526135
Synonyms: Tph2-lacZ
Gene: Tph2  Location: Chr10:114914546-115020927 bp, - strand  Genetic Position: Chr10, 63.51 cM
Alliance: Tph2tm1Kry page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:240993
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    A lacZ gene was inserted into the locus. No additional details are given. (J:240993)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tph2 Mutation:  41 strains or lines available
References
Original:  J:240993 Yadav VK, et al., A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell. 2009 Sep 04;138(5):976-89
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory