Trim40^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim40^em1Cya
• Name: tripartite motif-containing 40; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7526490
• Gene: Trim40 Location: Chr17:37192490-37201015 bp, - strand Genetic Position: Chr17, 19.16 cM
• Alliance: Trim40^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology targeted exon 1 for generation of a knock-out allele. (J:340161)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim40 Mutation: 14 strains or lines available

References

• Original: J:340161 Kang S, et al., TRIM40 is a pathogenic driver of inflammatory bowel disease subverting intestinal barrier integrity. Nat Commun. 2023 Feb 9;14(1):700
• All: 1 reference(s)