A1bg^em1Flc
Endonuclease-mediated Allele Detail

Summary

• Symbol: A1bg^em1Flc
• Name: alpha-1-B glycoprotein; endonuclease-mediated mutation 1, Frank Conlon
• MGI ID: MGI:7531168
• Synonyms: A1bg^flox
• Gene: A1bg Location: Chr15:60789438-60793119 bp, - strand Genetic Position: Chr15, 25.7 cM
• Alliance: A1bg^em1Flc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 4 to 7 were flanked by loxP sites via CRISPR/Cas9 technology. (J:314176)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any A1bg Mutation: 25 strains or lines available

References

• Original: J:314176 Shi W, et al., Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation. Dev Cell. 2021 Nov 8;56(21):3019-3034.e7
• All: 1 reference(s)