Acsl4^tm1.1Wgu
Targeted Allele Detail

Summary

• Symbol: Acsl4^tm1.1Wgu
• Name: acyl-CoA synthetase long-chain family member 4; targeted mutation 1.1, Wei Gu
• MGI ID: MGI:7532526
• Synonyms: acsl4^-
• Gene: Acsl4 Location: ChrX:141100989-141173531 bp, - strand Genetic Position: ChrX, 63.12 cM
• Alliance: Acsl4^tm1.1Wgu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282892
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the neo cassette and exon 2. (J:282892)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Acsl4 Mutation: 14 strains or lines available

References

• Original: J:282892 Chu B, et al., ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nat Cell Biol. 2019 May;21(5):579-591
• All: 2 reference(s)