In(2Itga6-Igs15)3Ddu
Targeted Allele Detail
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Symbol: |
In(2Itga6-Igs15)3Ddu |
Name: |
inversion, Chr 2, Denis Duboule 3 |
MGI ID: |
MGI:7537001 |
Synonyms: |
Inv(Itga6-Attp) |
Gene: |
In(2Itga6-Igs15)3Ddu Location: unknown Genetic Position: Chr2, Syntenic
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Germline Transmission: |
Earliest citation of germline transmission:
J:239094
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (No functional change) |
Mutation: |
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Inversion
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Mutation details: Mice with the Itga6tm1Son allele containing a single loxP site between exons 24 and 26 in cis on chromosome 2 and Igs15tm1.1Ddu, which also contains a loxP site integrated 3' of Hoxd1, were crossed to Hprttm1(cre)Mnn mice. Cre expression resulted in inversion of a segment of chromosome 2 containing exon 26 of Itga6 and the attp site 3' of Hoxd1.
(J:239094)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any In(2Itga6-Igs15)3Ddu Mutation: |
0 strains or lines available
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Original: |
J:239094 Schep R, et al., Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7720-E7729 |
All: |
2 reference(s) |
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