Il23a^em1Ktak
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il23a^em1Ktak
• Name: interleukin 23, alpha subunit p19; endonuclease-mediated mutation 1, Kiyoshi Takeda
• MGI ID: MGI:7539748
• Gene: Il23a Location: Chr10:128132009-128133953 bp, - strand Genetic Position: Chr10, 76.51 cM, cytoband D3
• Alliance: Il23a^em1Ktak page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 deleted 121 bp. (J:242021)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il23a Mutation: 25 strains or lines available

References

• Original: J:242021 Kitada S, et al., BATF2 inhibits immunopathological Th17 responses by suppressing Il23a expression during Trypanosoma cruzi infection. J Exp Med. 2017 May 01;214(5):1313-1331
• All: 2 reference(s)