Tor1atm1.1Rbro
Targeted Allele Detail
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Symbol: |
Tor1atm1.1Rbro |
Name: |
torsin family 1, member A (torsin A); targeted mutation 1.1, Robert M Brownstone |
MGI ID: |
MGI:7550827 |
Gene: |
Tor1a Location: Chr2:30850639-30857945 bp, - strand Genetic Position: Chr2, 21.77 cM
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Alliance: |
Tor1atm1.1Rbro page
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Germline Transmission: |
Earliest citation of germline transmission:
J:340335
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6J
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: The targeting construct flanked exons 3 to 5 with FRT sites and inserted a loxP flanked neomycin resistance cassette. Recombination removed the selection cassette.
(J:340335)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tor1a Mutation: |
24 strains or lines available
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Original: |
J:340335 Pocratsky AM, et al., Pathophysiology of Dyt1-Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction. Sci Transl Med. 2023 May 3;15(694):eadg3904 |
All: |
1 reference(s) |
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