Gt(ROSA)26Sor^{tm1(Trib1,-EGFP)Ekt}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Trib1,-EGFP)Ekt}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Endre Kiss-Toth
• MGI ID: MGI:7564258
• Synonyms: Trib1^{mTransgenic (Tg)}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Trib1,-EGFP)Ekt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283301
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into the locus a splice acceptor, floxed neomycin resistance/STOP cassette, the mouse gene, FRT-flanked IRES and EGFP reporter gene, and polyadenylation sequence. (J:283301)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:283301 Johnston JM, et al., Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion. Sci Adv. 2019 Oct;5(10):eaax9183
• All: 1 reference(s)