Tslp^em1Dlsa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tslp^em1Dlsa
• Name: thymic stromal lymphopoietin; endonuclease-mediated mutation 1, David L Sacks
• MGI ID: MGI:7565343
• Synonyms: Tslp^f
• Gene: Tslp Location: Chr18:32948436-32952850 bp, + strand Genetic Position: Chr18, 18.12 cM
• Alliance: Tslp^em1Dlsa page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 1 and 2 were flanked by loxP sites via CRISPR/Cas9 technology. (J:343267)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tslp Mutation: 14 strains or lines available

References

• Original: J:343267 Lee SH, et al., Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis. Nat Commun. 2023 Nov 29;14(1):7852
• All: 1 reference(s)