Del(16Mir802-Vps26c)4TybEmcf
Targeted Allele Detail

Summary

• Symbol: Del(16Mir802-Vps26c)4TybEmcf
• Name: deletion, Chr 16, Victor Tybulewicz and Elizabeth M C Fisher 4
• MGI ID: MGI:7571187
• Synonyms: Del(16)4TybEmcf
• Gene: Del(16Mir802-Vps26c)4TybEmcf Location: unknown Genetic Position: Chr16, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:343786
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intergenic deletion
• Del(16Mir802-Vps26c)4TybEmcf involves 48 genes/genome features (Mir802, 1700029J03Rik, Gm30695 ...) View all
• Mutation details: An un-specified MICER vector and MHPP432c09 (16:94538615-16:94546849 Mb; mouse assembly GRCm38/mm10) located between Dscr3 and Dyrk1a were subjected to cre-mediated recombination to delete the sequence flanked by loxP sites. (J:343786)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(16Mir802-Vps26c)4TybEmcf Mutation: 0 strains or lines available

References

• Original: J:343786 Lana-Elola E, et al., Congenital heart defects in Down syndrome are caused by increased dosage of DYRK1A. bioRxiv. 2023
• All: 1 reference(s)