Tg(Ins2-CAST)1Ksp
Transgene Detail

Summary

• Symbol: Tg(Ins2-CAST)1Ksp
• Name: transgene insertion 1, Kenneth S Polonsky
• MGI ID: MGI:7571413
• Transgene: Tg(Ins2-CAST)1Ksp Location: unknown
• Alliance: Tg(Ins2-CAST)1Ksp page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ins2-CAST)1Ksp expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CAST (831)

  Cast	(MGI:1098236)

• Tg(Ins2-CAST)1Ksp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• The rat insulin 2 promoter was used to drive the expression of human calpastatin gene. (J:123988)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:123988 Johnson JD, et al., RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets. J Biol Chem. 2004 Jun 4;279(23):24794-802
• All: 2 reference(s)