Flvcr1^tm2Etol
Targeted Allele Detail

Summary

• Symbol: Flvcr1^tm2Etol
• Name: feline leukemia virus subgroup C cellular receptor 1; targeted mutation 2, Emanuela Tolosano
• MGI ID: MGI:7580692
• Synonyms: Flvcr1a^fl
• Gene: Flvcr1 Location: Chr1:190738044-190758355 bp, - strand Genetic Position: Chr1, 96.28 cM
• Alliance: Flvcr1^tm2Etol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:315525
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 1. Flp-mediated recombination removed the selection cassette. (J:315525)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Flvcr1 Mutation: 30 strains or lines available

References

• Original: J:315525 Vinchi F, et al., Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450. Gastroenterology. 2014 May;146(5):1325-38
• All: 5 reference(s)