Tg(Scgb1a1-Muc5ac/GFP)1Bouc
Transgene Detail

Summary

• Symbol: Tg(Scgb1a1-Muc5ac/GFP)1Bouc
• Name: transgene insertion 1, Richard Boucher
• MGI ID: MGI:7593814
• Synonyms: Muc5ac-Tg
• Transgene: Tg(Scgb1a1-Muc5ac/GFP)1Bouc Location: unknown
• Alliance: Tg(Scgb1a1-Muc5ac/GFP)1Bouc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Scgb1a1-Muc5ac/GFP)1Bouc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Muc5ac (MGI:104697)

• Tg(Scgb1a1-Muc5ac/GFP)1Bouc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Scgb1a1 (25575)

  Scgb1a1

  (MGI:98919)

• Mutation details: A GFP coding sequence was inserted in-frame into the middle of the mouse Muc5ac coding sequence just 5 to the sequences encoding the variable numbers of tandem repeats (VNTR) domain. The expression of the fusion gene product was placed under the control of the rat Clara cell secretory protein (Scgb1a1) promoter. (J:190329)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:190329 Ehre C, et al., Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs. (correction). Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16528-33
• All: 1 reference(s)