Tg(tetO-EGFP/Oga*)1Jkuab
Transgene Detail

Summary

• Symbol: Tg(tetO-EGFP/Oga*)1Jkuab
• Name: transgene insertion, Andrew J Paterson
• MGI ID: MGI:7608445
• Synonyms: TetRE-NCOAT(GK)
• Transgene: Tg(tetO-EGFP/Oga*)1Jkuab Location: unknown
• Alliance: Tg(tetO-EGFP/Oga*)1Jkuab page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains the tetracycline-responsive element driving inducible expression of a chimera of the short GK NCOAT sequence (350-1110) from rat inserted into the corresponding mouse sequence (350-1400) using unique BlpI-NcoI restriction sites. Four founders were generated. Line 1 is the representative line. (J:134284)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:134284 Whisenhunt TR, et al., Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development. Glycobiology. 2006 Jun;16(6):551-63
• All: 3 reference(s)