Hbb-bt^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hbb-bt^em1(IMPC)J
• Name: hemoglobin, beta adult t chain; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7643239
• Gene: Hbb-bt Location: Chr7:103461731-103463130 bp, - strand Genetic Position: Chr7, Syntenic
• Alliance: Hbb-bt^em1(IMPC)J page
• IMPC: Hbb-bt gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences: ATAAGTGGTGAGATAGTAAG and ATGACAACCATATCTACACA. This resulted in a 1,769 bp deletion of Chr7:103,812,287-103,814,055(GRCm38/mm10) that removes exons ENSMUSE00000633129 through ENSMUSE00000633127. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Hbb-bt Mutation: 3 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)