Del(7Cyp2b10-Cyp2b9)1Fatso
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(7Cyp2b10-Cyp2b9)1Fatso
• Name: deletion, Chr 7, William Baldwin
• MGI ID: MGI:7703440
• Synonyms: Cyp2b10^{em1(Del(7Cyp2b10-Cyp2b9))Fatso}
• Gene: Del(7Cyp2b10-Cyp2b9)1Fatso Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Del(7Cyp2b10-Cyp2b9)1Fatso involves 12 genes/genome features (Cyp2b10, Cyp2b28-ps, Gm45227 ...) View all
• CRISPR-targeting deleted a 287kb segment including Cyp2b10, Cyp2b13, and Cyp2b9. (J:247967)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Del(7Cyp2b10-Cyp2b9)1Fatso Mutation: 2 strains or lines available

References

• Original: J:247967 Kumar R, et al., Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice. PLoS One. 2017;12(3):e0174355
• All: 5 reference(s)