Slmap^tm1.2Tuab
Targeted Allele Detail

Summary

• Symbol: Slmap^tm1.2Tuab
• Name: sarcolemma associated protein; targeted mutation 1.2, Balwant S Tuana
• MGI ID: MGI:7780106
• Gene: Slmap Location: Chr14:26134323-26256086 bp, - strand Genetic Position: Chr14, 16.09 cM, cytoband B
• Alliance: Slmap^tm1.2Tuab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:355261
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified isoform(s))
• Mutations: Insertion, Intragenic deletion
• Mutation details: LoxP sites were inserted around exon 3 via homologous recombination. This targets the Slmap3 isoforms with a start sites in exons 2 or 3 while leaving intact Slmap1 and Slmap2 isoforms with start sites in exon 10 and exon 16, respectively. Cre-mediated recombination removed exon 3. (J:355261)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slmap Mutation: 70 strains or lines available

References

• Original: J:355261 Rehmani T, et al., SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP. Life Sci Alliance. 2024 Dec;7(12)
• All: 1 reference(s)