Gt(ROSA)26Sor^{tm16(CAG-flpe)Ics}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm16(CAG-flpe)Ics}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 16, Mouse Clinical Institute
• MGI ID: MGI:7788436
• Synonyms: Gt(ROSA)26Sortm16(CAG-Flpe, HygR)ICS
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm16(CAG-flpe)Ics} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: BD10 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, Endonuclease)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm16(CAG-flpe)Ics} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: The following elements were inserted into an intron: an FRT site, the CAG promoter, flpe endonuclease cDNA, beta-globin poly(A) signal sequence, a hygromycin reistance gene cassette, and an F3 site. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1040 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)