Phenotypes Associated with This Genotype

Genotype
MGI:2169030

• Allelic Composition: Flt1^tm1Jrt/Flt1^tm1Jrt
• Genetic Background: either: (involves: 129/Sv) or (involves: CD-1) or (involves: ICR)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo development ( J:54830 )

• at E7.0, mice exhibit increased number of hemangioblasts compared with wild-type mice

• at E8.5, the number of endothelial cells is increased compared to in wild-type mice

• at E8.5, mice exhibit an increase in primary erythrocytes compared with wild-type mice

• altered cell differentiation leads to increased number of hemangioblasts compared to in wild-type mice

hematopoietic system

increased hemangioblast number ( J:54830 )

• at E7.0, mice exhibit increased number of hemangioblasts compared with wild-type mice

abnormal embryonic erythrocyte morphology ( J:54830 )

• at E8.5, mice exhibit an increase in primary erythrocytes compared with wild-type mice