Phenotypes Associated with This Genotype

Genotype
MGI:2175206

• Allelic Composition: Pax6^Sey-H/Pax6⁺
• Genetic Background: involves: 101/H * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reduced female fertility ( J:8534 )

♀ • females are poor breeders

♀ • however, some embryo death may be associated with prenatal lethality

vision/eye

coloboma ( J:8534 )

• mice often develop coloboma visible by day 14

microphthalmia ( J:8534 )

hearing/vestibular/ear

lowered ear position ( J:8534 )

• one or both ears

small ears ( J:8534 )

• one or both ears

growth/size/body

lowered ear position ( J:8534 )

• one or both ears

small ears ( J:8534 )

• one or both ears

decreased body size ( J:8534 )

• at 2.5 weeks mice are smaller than normal

craniofacial

lowered ear position ( J:8534 )

• one or both ears

small ears ( J:8534 )

• one or both ears

pigmentation

belly spot ( J:8534 )

• some mice may have a white belly spot or streak

integument

belly spot ( J:8534 )

• some mice may have a white belly spot or streak