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Phenotypes Associated with This Genotype
Genotype
MGI:2176382
Allelic
Composition
Pdyntm1Ute/Pdyntm1Ute
Genetic
Background
involves: 129S4/SvJae * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdyntm1Ute mutation (1 available); any Pdyn mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• small but significant decrease in tail flick response latency
• enhanced second phase paw flinch response after injection of 2% formalin
• increased sensitivity to mechanical stimulation after spinal nerve ligation at L5/L6 returned to normal by day 14 after surgery rather than persisting as in controls
• increased sensitivity to heat stimulation after spinal nerve ligation at L5/L6 returned to normal by day 9 after surgery rather than persisting as in controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory