Phenotypes Associated with This Genotype

Genotype
MGI:2176382

• Allelic Composition: Pdyn^tm1Ute/Pdyn^tm1Ute
• Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal touch/ nociception ( J:67584 )

abnormal response to tactile stimuli ( J:67584 )

• small but significant decrease in tail flick response latency

• enhanced second phase paw flinch response after injection of 2% formalin

• increased sensitivity to mechanical stimulation after spinal nerve ligation at L5/L6 returned to normal by day 14 after surgery rather than persisting as in controls

abnormal thermal nociception ( J:67584 )

• increased sensitivity to heat stimulation after spinal nerve ligation at L5/L6 returned to normal by day 9 after surgery rather than persisting as in controls