Phenotypes Associated with This Genotype

Genotype
MGI:2178666

• Allelic Composition: Hoxa9^tm1Mrc/Hoxa9^tm1Mrc; Hoxb9^tm1Mrc/Hoxb9^tm1Mrc
• Genetic Background: involves: 129S7/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

sternum hypoplasia ( J:37847 )

• sternum is hypoplastic and the length of all the intercostal segments is reduced and malformed

increased rib number ( J:37847 )

• 56% exhibit an extra articulating eighth rib

• 100% exhibit an extra pair of fully-grown ribs on the 21st vertebra

rib fusion ( J:37847 )

• 100 % exhibit bilateral fusions of first and second ribs that are more severe than in single homozygous mutant mice

• third rib fused to first and second rib fusion, incomplete penetrance