Phenotypes for Inhba Inhbb MGI:2180166 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Inhba^tm1Zuk/Inhba^tm1Zuk Inhbb^tm1Jae/Inhbb^tm1Jae
Genetic Background	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Inhba^tm1Zuk mutation (2 available); any Inhba mutation (31 available)
Inhbb^tm1Jae mutation (3 available); any Inhbb mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

neonatal lethality, incomplete penetrance ( J:23923 )

• 3 of 9 mice (33%) die from cleft secondary palates

craniofacial

absent incisors ( J:23923 )

cleft secondary palate ( J:23923 )

• 3 of 9 mice (33%) die from cleft secondary palates

vision/eye

eyelids open at birth ( J:23923 )

digestive/alimentary system

cleft secondary palate ( J:23923 )

• 3 of 9 mice (33%) die from cleft secondary palates

integument

absent vibrissae ( J:23923 )

growth/size/body

absent incisors ( J:23923 )

cleft secondary palate ( J:23923 )

• 3 of 9 mice (33%) die from cleft secondary palates

skeleton

absent incisors ( J:23923 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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