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Phenotypes Associated with This Genotype
Genotype
MGI:2651603
Allelic
Composition
Prkcetm1Msg/Prkcetm1Msg
Tg(Prnp-tTA)F959Sbp/0
Tg(tetO-Prkce)T9Msg/0
Genetic
Background
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkcetm1Msg mutation (1 available); any Prkce mutation (40 available)
Tg(Prnp-tTA)F959Sbp mutation (1 available)
Tg(tetO-Prkce)T9Msg mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• in mice administered doxycycline for 2 weeks, restoration of wild-type drinking behavior
• increased duration of regaining ethanol-induced loss or righting response, increase in duration of pentobarbital-induced loss or righting response


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory