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Phenotypes Associated with This Genotype
Genotype
MGI:2652241
Allelic
Composition		 Apex1tm1Ecf/Apex1+
Xpctm1Ecf/Xpctm1Ecf
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apex1tm1Ecf mutation (0 available); any Apex1 mutation (16 available)
Xpctm1Ecf mutation (1 available); any Xpc mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor incidence ( J:70397 )
• 16% developed microscopic tumors

cellular
oxidative stress ( J:70397 )
• increased sensitivity to oxidative stress

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory