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Phenotypes Associated with This Genotype
Genotype
MGI:2653174
Allelic
Composition
Zp2tm1Dean/Zp2tm1Dean
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * CF-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zp2tm1Dean mutation (5 available); any Zp2 mutation (49 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• disorganized cumulus-oocyte-complex
• reduced number of antral follicles relative to wild-type

reproductive system
• a thin zona pellucida is observed in pre-antral follicles, but not in the later stages of folliculogenesis
• disorganized cumulus-oocyte-complex
• reduced number of antral follicles relative to wild-type
• after hormonal stimulation, the number of eggs ovulated was <5% that in wild-type mice

cellular
• a thin zona pellucida is observed in pre-antral follicles, but not in the later stages of folliculogenesis


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory