Phenotypes Associated with This Genotype

Genotype
MGI:2653628

• Allelic Composition: Tg(H2-Ea-Il7)10Rhdr/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal double-negative T cell morphology ( J:81133 )

• 5.3% of double negative cells in 6 week old thymus are CD19+, a significant increase compared to controls

abnormal B cell morphology ( J:81133 )

• proportion of pro/pre-B cells in the thymus is significantly increased

immune system

abnormal double-negative T cell morphology ( J:81133 )

• 5.3% of double negative cells in 6 week old thymus are CD19+, a significant increase compared to controls

abnormal B cell morphology ( J:81133 )

• proportion of pro/pre-B cells in the thymus is significantly increased