Phenotypes Associated with This Genotype

Genotype
MGI:2663922

• Allelic Composition: Mos^tm1Sia/Mos^tm1Sia
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased teratoma incidence ( J:19086 )

• high frequency of ovarian teratomas

reproductive system

abnormal female meiosis ( J:19086 )

♀ • oocyte development failed to arrest during meiosis, leading to spontaneous parthenogenetic activation

female infertility ( J:19086 )

♀ • 10 of 25 females tested were infertile

reduced female fertility ( J:19086 )

♀ • females that are fertile have fewer and smaller litters compared with heterozygous females

decreased litter size ( J:19086 )

cellular

abnormal female meiosis ( J:19086 )

♀ • oocyte development failed to arrest during meiosis, leading to spontaneous parthenogenetic activation