Phenotypes Associated with This Genotype

Genotype
MGI:2676599

• Allelic Composition: Kcnj9^tm1Kwn/Kcnj9^tm1Kwn
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal synaptic transmission ( J:77047 )

• resting membrane potentials of locus ceruleus neurons in brain slices are depolarized by 15-20 mV relative to neurons from wild-type mice

behavior/neurological

behavior/neurological phenotype ( J:77047 )

N • mice are fertile and of normal size, exhibit normal coordination and show no abnormal feeding behavior, grooming, or responses to visual or auditory cues

N • no observed propensity for spontaneous and lethal seizures