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Phenotypes Associated with This Genotype
Genotype
MGI:2683967
Allelic
Composition
Gata3tm1Iho/Gata3tm1Iho
Tg(Cd4-cre)1Cwi/0
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata3tm1Iho mutation (0 available); any Gata3 mutation (32 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• thymocytes do not mature to the single positive stage
• percentage of single positive CD4 thymocytes is reduced from 10-15% in controls to 3% or less in mutants

immune system
• thymocytes do not mature to the single positive stage
• percentage of single positive CD4 thymocytes is reduced from 10-15% in controls to 3% or less in mutants


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory