Phenotypes Associated with This Genotype

Genotype
MGI:2684204

• Allelic Composition: Lepr^db-5J/Lepr^db-5J
• Genetic Background: NOD/ShiLtJ-Lepr^db-5J/LtJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

degranulated pancreatic beta cells ( J:87061 )

• beta-degranulation in the islets of Langerhans

pancreatic islet hyperplasia ( J:87061 )

growth/size/body

obese ( J:87061 )

• both males and females are obese by weaning age

homeostasis/metabolism

hyperglycemia ( J:87061 )

• age of onset by 5 weeks

increased circulating insulin level ( J:87061 )