Phenotypes Associated with This Genotype

Genotype
MGI:3029187

• Allelic Composition: Trpv1^tm1Jbd/Trpv1^tm1Jbd
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal nociception after inflammation ( J:62074 )

• while mice did not show a prolonged latency in the hot plate test, they did not develop thermal hyperalgesia after induced inflammation by carrageenan injection

abnormal thermal nociception ( J:62074 )

nervous system

abnormal nervous system electrophysiology ( J:62074 )

• cultured small dorsal root ganglion neurons lacked capsaicin-, acid-, and heat-gated responses, but exhibited normal responses to gamma-aminobutyric acid and ATP