Phenotypes Associated with This Genotype

Genotype
MGI:3029402

• Allelic Composition: Prkaa1^tm1Sbj/Prkaa1^tm1Sbj
• Genetic Background: involves: 129S2/SvPas * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

decreased muscle cell glucose uptake ( J:87719 )

• contraction-stimulated glucose uptake is decreased by about 25% in soleus muscle, but not in extensor digitorum longus (EDL) muscle

• however, normal 5-aminoimidazole-4-carboxamide-1-beta-4 ribofuranoside (AICAR)-induced glucose uptake in skeletal muscle

cellular

decreased muscle cell glucose uptake ( J:87719 )

• contraction-stimulated glucose uptake is decreased by about 25% in soleus muscle, but not in extensor digitorum longus (EDL) muscle

• however, normal 5-aminoimidazole-4-carboxamide-1-beta-4 ribofuranoside (AICAR)-induced glucose uptake in skeletal muscle