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Phenotypes Associated with This Genotype
Genotype
MGI:3039405
Allelic
Composition
Emx2tm1Pgr/Emx2+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx2tm1Pgr mutation (0 available); any Emx2 mutation (23 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
• absence of the articulatory surface for the incus
• the inner hair cells were disorganized with an increased number of cells noted
• four rows of outer hair cells were present instead of three; a patchy arrangement was also noted

skeleton
• absence of the articulatory surface for the incus
• defects in the articulation between the incus and malleus; however, the ossicular chain did not appear to be affected

nervous system
• the inner hair cells were disorganized with an increased number of cells noted
• four rows of outer hair cells were present instead of three; a patchy arrangement was also noted

craniofacial
• absence of the articulatory surface for the incus


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory