Phenotypes Associated with This Genotype

Genotype
MGI:3041122

• Allelic Composition: Nrip1^tm1Mpk/Nrip1⁺
• Genetic Background: involves: 129/Ola

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:74971 )

♀N • heterozygous null ovaries displayed normal endocrine function

reproductive system

abnormal ovulation ( J:74971 )

♀ • heterozygous null mice showed an ovarian phenotype that was intermediate between wild-type and homozygous null mice

abnormal superovulation ( J:74971 )

♀ • ovarian sections from superovulated immature heterozygotes revealed luteinizing follicles with occasional hemorrhagic cysts; this phenotype was more pronounced in mature mice but to an intermediate extent relative to homozygous null mice

failure of superovulation ( J:74971 )

♀ • superovulation of heterozygous mice resulted in a failure of approximately 50% of the luteinizing follicles to release the oocyte