immune system
• compared to controls, reduced humoral response to T cell-independent antigen (NP-Ficoll), but not T cell-dependent antigen (NP-chick gamma-globulin conjugate)
• greater response than homozygous mutant mice, suggestive of gene dosage effects
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• IgG3 slightly reduced, compared to controls, but greater than homozygous mutant mice, suggestive of gene dosage phenomenon
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• slightly reduced, compared to controls, but greater than homozygous mutant mice, suggestive of gene dosage phenomenon
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hematopoietic system
• IgG3 slightly reduced, compared to controls, but greater than homozygous mutant mice, suggestive of gene dosage phenomenon
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• slightly reduced, compared to controls, but greater than homozygous mutant mice, suggestive of gene dosage phenomenon
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