Phenotypes Associated with This Genotype

Genotype
MGI:3042109

• Allelic Composition: Prkcg^tm1Stl/Prkcg^tm1Stl
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

alcohol preference ( J:79995 )

• ingested more ethanol than controls, but no greater consumption of liquid volume

• while both males and females consumed more ethanol than controls, females consumed more than males

impaired behavioral response to alcohol ( J:54243 )

• lack of tolerance to sedative-hypnotic effects of chronic (10 day) ethanol diet

• developed chronic hypothermia tolerance after 10 day ethanol diet

decreased anxiety-related response ( J:64043 )

• in elevated plus-maze, black/white box, and mirrored chamber

• baseline locomotor activity is similar to controls

abnormal impulsive behavior control ( J:79995 )

• greater behavioral impulsivity in appetitive-signaled nosepoke test

taste/olfaction

taste/olfaction phenotype ( J:79995 )

N • saccharin preference similar to controls

N • nicotine consumption similar to controls