Phenotypes Associated with This Genotype

Genotype
MGI:3043149

• Allelic Composition: Pdyn^tm1Ute/Pdyn^tm1Ute
• Genetic Background: B6.129S4-Pdyn^tm1Ute

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired conditioned place preference behavior ( J:84344 )

• mutant mice exhibit much lower response than controls in cocaine place preference tests

abnormal anxiety-related response ( J:84344 )

• forced swim test had no effect on tail withdrawl latency unlike controls where latency increased

decreased anxiety-related response ( J:84344 )

• reduced immobility on second and later forced swim test trials

• swim stressed mice were much like unstressed mice