Phenotypes Associated with This Genotype

Genotype
MGI:3044039

• Allelic Composition: Ppp3r1^tm2.1Grc/Ppp3r1^tm2.1Grc
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:89771 )

• mice died at E11 due to defects in vascular patterning

• phenotype is stated to be identical to that of Ppp3r1^tm2.1Grc homozygotes; however no data is presented in J:89771

embryo

decreased embryo size ( J:89771 )

abnormal extraembryonic tissue morphology ( J:89771 )

• phenotype is stated to be identical to that of Ppp3r1^tm2.1Grc homozygotes; however no data is presented in J:89771

absent vitelline blood vessels ( J:89771 )

abnormal visceral yolk sac morphology ( J:89771 )

disorganized yolk sac vascular plexus ( J:89771 )

growth/size/body

decreased embryo size ( J:89771 )

cardiovascular system

abnormal blood vessel morphology ( J:89771 )

• phenotype is stated to be identical to that of Ppp3r1^tm2.1Grc homozygotes; however no data is presented in J:89771

abnormal angiogenesis ( J:89771 )

absent vitelline blood vessels ( J:89771 )

disorganized yolk sac vascular plexus ( J:89771 )

abnormal heart morphology ( J:89771 )

• phenotype is stated to be identical to that of Ppp3r1^tm2.1Grc homozygotes; however no data is presented in J:89771

distended pericardium ( J:89771 )