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Phenotypes Associated with This Genotype
Genotype
MGI:3044359
Allelic
Composition		 Hsf1tm1Anak/Hsf1tm1Anak
Genetic
Background		 involves: C57BL/6 * CBA * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hsf1tm1Anak mutation (1 available); any Hsf1 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:89846 )
N
• homozygous males are fertile with testes of normal weight and histologically normal as well
abnormal spermatogenesis ( J:89846 )
• apoptosis in seminiferous tubules of heat shocked testes was considerably reduced as compared to controls
• few late pachytene spermatocytes die as a result of heat stress

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory