About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3044773
Allelic
Composition		 Sigmar1tm1Lmon/Sigmar1tm1Lmon
Genetic
Background		 either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) or (involves: 129S1/Sv * 129X1/SvJ * CD-1)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sigmar1tm1Lmon mutation (2 available); any Sigmar1 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased locomotor activity ( J:89669 )
• mean mobile time during spontaneous activity is significantly lower for homozygous mutants
• a receptor agonist (SKF-10 047) fails to induce hyperactivity in homozygous mutant mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory