Phenotypes Associated with This Genotype

Genotype
MGI:3046635

• Allelic Composition: Bmpr1a^tm2Bhr/Bmpr1a^tm2Bhr; Tg(KRT14-cre)52Smr/0
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

absent teeth ( J:91054 )

mortality/aging

postnatal lethality, complete penetrance ( J:91054 )

• die within first 4 days

behavior/neurological

abnormal suckling behavior ( J:91054 )

• difficulty suckling

craniofacial

abnormal mouth morphology ( J:91054 )

• oral abnormalities resulting from defective tooth development

absent teeth ( J:91054 )

growth/size/body

abnormal mouth morphology ( J:91054 )

• oral abnormalities resulting from defective tooth development

absent teeth ( J:91054 )

decreased body size ( J:91054 )

• severely runted

integument

abnormal hair growth ( J:91054 )

alopecia ( J:91054 )

• lacked external hair

abnormal hair shaft morphology ( J:91054 )

• shafts usually fail to form in follicles

abnormal hair follicle morphology ( J:91054 )

• wavy

abnormal hair follicle dermal papilla morphology ( J:91054 )

• misshapen and expanded dermal papillae

abnormal hair follicle orientation ( J:91054 )

• misangled

• not as deep into the dermis

small hair follicles ( J:91054 )