Phenotypes for Dab1 Reln MGI:3050790 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Dab1^tm1Cpr/Dab1^tm4Cpr Reln^rl/Reln⁺
Genetic Background	involves: 129/Sv * C3HeB/Fe * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dab1^tm1Cpr mutation (1 available); any Dab1 mutation (79 available)
Dab1^tm4Cpr mutation (0 available); any Dab1 mutation (79 available)
Reln^rl mutation (3 available); any Reln mutation (209 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal cortical marginal zone morphology ( J:91679 )

• the marginal zone of the cortex is reduced, similar to compound heterozygous mice wild-type for Reln

abnormal hippocampus morphology ( J:91679 )

• the hippocampus is subtly disorganized in the CA2/3 region compared to mice heterozygous for Dab1^tm1Cpr and Reln^rl

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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