Phenotypes Associated with This Genotype

Genotype
MGI:3053805

• Allelic Composition: Rad9a^tm1Lieb/Rad9a^tm1Lieb
• Genetic Background: involves: 129S/SvEv * Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:92282 )

• homozygous embryos die between E9.5 and E12.5

embryo

embryonic growth arrest ( J:92282 )

• By E8.5 many areas undergoing apoptosis

abnormal embryonic tissue morphology ( J:92282 )

• By E7.5 embryos consistently smaller than wild-type

• By E.85 most regions, including heart and brain are underdeveloped and caudal extremity of embryo is stunted