Phenotypes Associated with This Genotype

Genotype
MGI:3055851

• Allelic Composition: Ercc1^tm1Jhjh/Ercc1^tm1Jhjh
• Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:41161 )

• mutants do not live beyond 38 days of age

embryonic lethality during organogenesis, incomplete penetrance ( J:41161 )

• many mutant embryos die by E13.5

growth/size/body

embryonic growth retardation ( J:41161 )

• on a mixed 129P2/OlaHsd and C57BL/6 background embryonic growth delay is seen

decreased body size ( J:41161 )

• homozygotes are severely runted

embryo

embryonic growth retardation ( J:41161 )

• on a mixed 129P2/OlaHsd and C57BL/6 background embryonic growth delay is seen