Phenotypes Associated with This Genotype

Genotype
MGI:3055984

• Allelic Composition: Nudt1^tm1Tts/Nudt1^tm1Tts
• Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased stomach tumor incidence ( J:71836 )

• lesions of the glandular stomach are 3 times as frequent as in controls

• adenomatous hyperplasia, adenomas, and adenocarcinoma

increased liver tumor incidence ( J:71836 )

• liver tumors in 38% of males as opposed to 13% of control males

• liver tumors in 3.9% of females as opposed to none in female controls

increased lung adenoma incidence ( J:71836 )

• found in greater numbers at age 1.5 years

increased lung adenocarcinoma incidence ( J:71836 )

• found in greater numbers at age 1.5 years

digestive/alimentary system

increased stomach tumor incidence ( J:71836 )

• lesions of the glandular stomach are 3 times as frequent as in controls

• adenomatous hyperplasia, adenomas, and adenocarcinoma

respiratory system

increased lung adenoma incidence ( J:71836 )

• found in greater numbers at age 1.5 years

increased lung adenocarcinoma incidence ( J:71836 )

• found in greater numbers at age 1.5 years

liver/biliary system

increased liver tumor incidence ( J:71836 )

• liver tumors in 38% of males as opposed to 13% of control males

• liver tumors in 3.9% of females as opposed to none in female controls