Phenotypes for Sox10 MGI:3513122 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Sox10^tm2(rtTA)Weg/Sox10⁺
Genetic Background	involves: 129P2/OlaHsd

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox10^tm2(rtTA)Weg mutation (0 available); any Sox10 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:94207 )

belly spot ( J:94207 )

• with increasing numbers of backcrosses, nearly all heterozygotes developed a white belly spot

digestive/alimentary system

megacolon ( J:94207 )

• in early backcrosses, a few heterozygotes developed megacolon

integument

abnormal coat/hair pigmentation ( J:94207 )

belly spot ( J:94207 )

• with increasing numbers of backcrosses, nearly all heterozygotes developed a white belly spot

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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