Analysis Tools
reproductive system
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• despite an absence of synapsis between homologs in spermatocytes, 28%-35% of spermatocytes exhibit homolog pairing in the chromosome mid- and subtelomeric regions
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• no spematocyte nuclei with 19 fully synapsed autosomes are detected
(J:94208)
• regional splitting of axial elements is seen at the early zygotene stage but is suppressed in later stages when double-strand break markers accumulate in spermatocytes
(J:209347)
|
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• spermatogenesis arrests at meiotic prophase I with no postmeiotic spermatids seen in the seminiferous tubules
(J:94208)
• spermatocytes form axial elements but they arrest at the leptotene/zygotene stage
(J:209347)
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• spermatocytes form axial elements but they arrest at the leptotene/zygotene stage with aberrant synaptonemal complex formation
|
small ovary
(
J:94208
)
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• only residual ovaries are seen in 6 week old females
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small testis
(
J:94208
)
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• at 5-6 weeks of age mutant testis are about 50% the size of wild-type
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infertility
(
J:94208
)
|
• both males and females are infertile
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endocrine/exocrine glands
small ovary
(
J:94208
)
|
|
• only residual ovaries are seen in 6 week old females
|
small testis
(
J:94208
)
|
|
• at 5-6 weeks of age mutant testis are about 50% the size of wild-type
|
cellular
|
|
• despite an absence of synapsis between homologs in spermatocytes, 28%-35% of spermatocytes exhibit homolog pairing in the chromosome mid- and subtelomeric regions
|
|
|
• no spematocyte nuclei with 19 fully synapsed autosomes are detected
(J:94208)
• regional splitting of axial elements is seen at the early zygotene stage but is suppressed in later stages when double-strand break markers accumulate in spermatocytes
(J:209347)
|
|
|
• spermatogenesis arrests at meiotic prophase I with no postmeiotic spermatids seen in the seminiferous tubules
(J:94208)
• spermatocytes form axial elements but they arrest at the leptotene/zygotene stage
(J:209347)
|
|
|
• spermatocytes form axial elements but they arrest at the leptotene/zygotene stage with aberrant synaptonemal complex formation
|
